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Adapalene (Differin) Gel 0.1% Acne Treatment Trial

#63
Today marks 8 weeks since I started the treatment.

Last weekend, I took a break from acne treatments because I was experiencing some tightness/irritation. It was probably due to my having combined adapalene and benzoyl peroxide in a single routine over the last 4 weeks, and having worked up to daily use of them that way, which was apparently too much for me. As a result, I discontinued salicylic acid in place of adapalene for daytime use, and I now reserve benzoyl peroxide for the night. My reasoning?
  1. Adapalene is stable in that it can be applied during the day without degrading.
  2. I’ve begun shaving at night, and it would be counterproductive to compound exfoliation with a leave-on exfoliant when that is exactly what I’m trying to avoid with this modified routine. Benzoyl peroxide is widely available in wash-off products, which is how I intend to use it before I shave. (Well, I’d still be compounding exfoliation but to a much milder extent.)
Anyway, you’re probably teetering at the edge of your seat/bed with suspense regarding my progress. It’s nothing to fall on your ass over, but it is a marked improvement. My left cheek, which has typically been the site of my most severe breakouts, has remained clear since my prior update, and I believe that it was clear even then. I’ve sustained a few spots, namely around my chin, but, like in my last report, I didn’t find myself picking at them nor paying them any more mind than I needed to. (One of them seems to be an ingrown hair anyway, which I’m indirectly treating with benzoyl peroxide.) On the whole, I’m content with my progress, and I expect greater improvement to follow in the coming months.
 

Walker

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#64
Anyway, you’re probably teetering at the edge of your seat/bed with suspense regarding my progress. It’s nothing to fall on your ass over, but it is a marked improvement.
I don't have acne and I still show up here to check this thread. Something about your writing keeps one returning like an enticing novel. How that's possible based on the subject matter, I have no idea.
 
#65
I don't have acne and I still show up here to check this thread. Something about your writing keeps one returning like an enticing novel. How that's possible based on the subject matter, I have no idea.
Oh, yay.

Well, hey. Maybe if/when someone whom you know is coping with an onset of acne, you can say “I may not have acne, but get a load of this nerd—“ as you direct him/her to my thread.
 

Walker

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#66
Well, hey. Maybe if/when someone whom you know is coping with an onset of acne, you can say “I may not have acne, but get a load of this nerd—“ as you direct him/her to my thread.
What I'm gonna do is rewrite this article https://www.suicideforum.com/2017/03/30/a-face-to-die-for-acne-and-suicide/
and coordinate your information or your thread or something into it. This thread / your knowledge of this topic is far too good to go to waste. I'd rather have you write the whole god damn article but you already said you'd rather eat a cockroach than do that. I'm gonna rope it in here somehow.
So yeah, totally going to point some nerds this way. And some cool people. And everyone else. That article is one of the top hitting articles of the entire site for some reason, gathering more views than almost any page here outside of the forums. Your information would be a huge help to others.
 
#67
What I'm gonna do is rewrite this article https://www.suicideforum.com/2017/03/30/a-face-to-die-for-acne-and-suicide/
and coordinate your information or your thread or something into it.
*anxiously fact-checks my information*
I'd rather have you write the whole god damn article but you already said you'd rather eat a cockroach than do that.
T-That’s not—okay.

Well, I’m sorry that I’m such a wuss, but damn: I wasn’t expecting a rewrite on that article to happen. Good luck incorporating my verbiage.
Your information would be a huge help to others.
I’m feeling inspired to continue contemplating acne skincare out loud.
 

Walker

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#68
*anxiously fact-checks my information*
Don't be silly. Just rewrite that article for me and it'll be fine. ;)

I wasn’t expecting a rewrite on that article to happen
I don't really know for sure that we're going to link to this thread exactly but christ you write this perfectly. How could someone showing up to the site, suicidal because of it, not wanna read this??

I’m feeling inspired to continue contemplating acne skincare out loud
I'm glad because I believe people are finding it useful ..and will continue to find this thread useful over a long period of time
 

Bloop

River Lea by Adele
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#69
Surprised to see a thread on this. When I saw the title I did a double take. I also use this, have been for a few years. Mine is a cream although I have used the gel as well. I use it along with a tablet and it has had a marked difference on my skin. My acne was most prominent on my back and face but I rarely get breakouts on my face anymore and it has helped a lot with my back. I used to wake up to bloody sheets every morning but haven't had that problem in a long while. The spots that are there aren't nearly as painful as the ones I had before I started my acne treatment. Adapalene, as you mentioned, does seem to help heal any breakouts remarkably quickly.
 
#70
My acne was most prominent on my back and face but I rarely get breakouts on my face anymore and it has helped a lot with my back.
Nice. I’d like to try this on my trunk, but it’s just such a large area for such a small quantity of product. I’d rather just use a systemic treatment like Isotretinoin, but, of course, that’s not up to me.

How do you apply adapalene cream on your back? Applicator? Hands?
I used to wake up to bloody sheets every morning but haven't had that problem in a long while.
That had to be distressing.
The spots that are there aren't nearly as painful as the ones I had before I started my acne treatment.
I know the feeling. Benzoyl peroxide helped me in that manner, but the acne and dark spots still persist.
 

Innocent Forever

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#71
I think my face isn't as bad. It would be interesting to see because as of now I'm still getting acne everywhere, though it's not as bad as it could be (the 4 spots on the roof of my mouth have finally gone). The lymecycline obviously hasn't yet made a difference. Or not too much of a difference. If the acne mostly clears where I'm using epiduo, and doesn't come back, we know it works.

@Inanimate I meant my offer of sending you epi. If you're interested let me know how to... - if it's worth it for you to.
 

Bloop

River Lea by Adele
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#72
Nice. I’d like to try this on my trunk, but it’s just such a large area for such a small quantity of product. I’d rather just use a systemic treatment like Isotretinoin, but, of course, that’s not up to me.

How do you apply adapalene cream on your back? Applicator? Hands?

That had to be distressing.

I know the feeling. Benzoyl peroxide helped me in that manner, but the acne and dark spots still persist.
It has been a bit of a stretch in the past 1 cream for 1 month but as the spots came down I started applying smaller amounts each day and ended up on 1x cream for 2 months. But now I've grown a cool looking (but very thick) beard they were happy to give me 2x cream for 2 months again.

After applying to my face I use the remainder on my back and then if there is anything left a bit on a small area centre of my chest. I can't reach so far down on my back but the spots have always been higher up so I don't have to reach when applying. It's made me feel a lot more at ease now that there is very few spots left there, they used to be quite big and painful. Had to avoid wearing light coloured tshirts, sitting back on sofa if they were likely to pop and things like that.

Few years back I was at a family friends dinner and was outside smoking and my dads friend was coming in from the garage and put his hands on my shoulders from behind in a friendly manner like hows things. It was quite painful and he let go very quickly. I didn't tell him it tell him that it hurt but he could feel the spots through my tshirt and probably could imagine lol

Nice not to worry about these things anymore. The tablet I'm on is lymecycline. Before that I was on doxycycline. Both worked well to bring down the spots but from my own testing over the years I've come to the conclusion that the cream is the real gem.
 
#73
I think my face isn't as bad. It would be interesting to see because as of now I'm still getting acne everywhere, though it's not as bad as it could be (the 4 spots on the roof of my mouth have finally gone). The lymecycline obviously hasn't yet made a difference. Or not too much of a difference. If the acne mostly clears where I'm using epiduo, and doesn't come back, we know it works.

@Inanimate I meant my offer of sending you epi. If you're interested let me know how to... - if it's worth it for you to.
Like I said in an earlier post, just use it daily, if tolerated, for a minimum of 3 months. You may as well since it’s growing from trees. *wink*

Speaking of which, I didn’t doubt you before, but I still decline. Nonetheless, I appreciate it.
 
#74
It has been a bit of a stretch in the past 1 cream for 1 month but as the spots came down I started applying smaller amounts each day and ended up on 1x cream for 2 months. But now I've grown a cool looking (but very thick) beard they were happy to give me 2x cream for 2 months again.
To my surprise, I’ve managed to use a 1 month supply strictly on my face for 2 months, and half of that time I’ve used it daily, yet I have quite a bit left.

Well, I’m failing to see the connection between a thick beard and a larger supply, but it has managed to make me completely envious.

I may bring the adapalene down to my neck and chest then, once or twice a week to start. Moisturizing apparently helps the acne heal by addressing the impaired skin barrier, so I’m starting to do that for my back post-shower again. Luckily, my left arm is highly flexible for no apparent reason, while my right is pitifully inflexible, so my upper back is ironically where I meet the most resistance.
Few years back I was at a family friends dinner and was outside smoking and my dads friend was coming in from the garage and put his hands on my shoulders from behind in a friendly manner like hows things. It was quite painful and he let go very quickly. I didn't tell him it tell him that it hurt but he could feel the spots through my tshirt and probably could imagine lol
So this is what social interaction gets you: literal pain.

Na, he seems pleasant, or at least considerate. Yes, at least this aspect of your reduced quality of is, for the most part, controlled. It’s a bitch when friction and acne are constants in your life.
The tablet I'm on is lymecycline. Before that I was on doxycycline. Both worked well to bring down the spots but from my own testing over the years I've come to the conclusion that the cream is the real gem.
It seems that topical retinoids are first-line treatments for a reason.
 

Innocent Forever

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#75
What cream are you using @Bloop ?

I haven't seen lymecycline help me at all, although last time I used it I did, however then I started with twice a day and used it for 6 months. Now it's been 3 months and only once a day.

@Inanimate I think the neck area is more sensitive. I tried it on my neck but got rashes.

I never thought of applying it to my shoulders because it's for the face. That's a really great idea. Thanks!
 

Bloop

River Lea by Adele
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#77
@Inanimate Getting the cream underneath my beard and onto the skin was a challenge using previous amounts. Mostly I would end up with a wet beard and nothing getting onto the skin which was causing large spots to form. Saying that, I don't need significantly more, 60 grams per 2 months would be suitable so I'll eventually have an oversupply of cream and go back down to 1 order per 2 months.

@Innocent Forever Adapalene (Differin) 0.1% w/w Cream 45g. I started it alongside Doxycycline for about 1.5 years before switching tablet to Lymecycline 6+ months ago. There was also a period I was prescribed gel (in the same amounts) instead of the cream. I checked the leaflet that comes with the cream and it says "It is used on the face, chest or back for acne..." so you should be okay using it like that.
 

Innocent Forever

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#78
@Inanimate Getting the cream underneath my beard and onto the skin was a challenge using previous amounts. Mostly I would end up with a wet beard and nothing getting onto the skin which was causing large spots to form. Saying that, I don't need significantly more, 60 grams per 2 months would be suitable so I'll eventually have an oversupply of cream and go back down to 1 order per 2 months.

@Innocent Forever Adapalene (Differin) 0.1% w/w Cream 45g. I started it alongside Doxycycline for about 1.5 years before switching tablet to Lymecycline 6+ months ago. There was also a period I was prescribed gel (in the same amounts) instead of the cream. I checked the leaflet that comes with the cream and it says "It is used on the face, chest or back for acne..." so you should be okay using it like that.
I feel like I tried differin once. No clue if I did it religiously or not. Now I'm using epiduo. If differin is working for you I doubt they'd change it. About lymecycline my GP isn't keen on it being used too constantly therefore has only given 1 repeat prescription so it will be for 6 months. I'm sure you've discussed it. Just throwing it out there....
 
#79
Getting the cream underneath my beard and onto the skin was a challenge using previous amounts. Mostly I would end up with a wet beard and nothing getting onto the skin which was causing large spots to form. Saying that, I don't need significantly more, 60 grams per 2 months would be suitable so I'll eventually have an oversupply of cream and go back down to 1 order per 2 months.
Oh, I see. I had assumed that you skipped the beard area altogether considering how difficult it can be to apply it there, which makes even less sense in retrospect.
 

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