I've been on lofepramine since october, I'm not sure if it was ever helping anyway but for the last few weeks I suddenly became very anxious again and pretty much shut myself away in my flat afraid to come out or speak to anyone. But the last couple of days I've had some rapid mood swings between that and feeling manic. Last night my thoughts were similar to if I were tripping. This reaction happened to me when I was put on citalopram 18 months ago, from the very first dose, and never got any better. I became a danger to myself. I'm worried about this happening. All day today I've felt really "high".