Does depression really make you tired?? How tired?? Do you stay that way?? Or snap out of it, until you feel down again?? I know I don't have much motivation,, well I hope that's not part of the problem in the way I feel.. I think I'm kind of bored with life and no doubt lonely from lack of having a relationship.. I know my fatigue doesn't come from depression, it started before I got that way, I'm being silly asking this. But just curious I guess to how bad depression can affect you physically.