I'm severely depressed too. (See my last few posts.) I have no answers. I can't take meds either. They make me really, really ill, like I've got the flu or something. I have severe allergies to everything, that's probably what it is. I'm allergic to the drugs too.:headache: Actually I've been reading lately that many types of inflammatory conditions are suspected of causing depression by causing inflammation in the brain. They are suspecting that the suicide rate goes up in late spring and summer because allergies get worse then. All my attempts have been in the late spring too. They also think that's why fish oil helps--it's an anti-inflammatory for the brain. They are researching the use of anti-inflammatory drugs now for depression. So if I take a med that gives me flu--like symptoms, which is inflammation, that's hardly very good for my depression is it? I was thinking of asking about that experimental operation where they implant electrodes into your brain (see past posts). They're even doing right in my own city. But I'm worried about getting an infection from any kind of operation. Ever since I developed allergic contact dermatitis the slightest injury to my skin, and I mean the absolute slightest injury, has to taken extremely good care of with sterilization and antibiotic ointment and bandaging for days or I will get a skin infection that threatens to go systemic without oral antibiotic use to get rid of it. So I figure having my skull cracked open might not be the safest thing under these circumstances. Actually I suspect that infection from an injury one day is going to kill me eventually, so why worry about doing it myself?