Weird. I was at 225 mg a day when I was 16, and I feel like it never helped with my depression or lack of concentration. When I initially started my dosage, I remember feeling just a touch dizzy, but that subsided and I felt no other side effects. No lack of sex drive, no dry mouth, and most of all, no lack of overwhelming depression.
I went off the effexor fairly quickly, years later. I think my doctor advised me as the manufacturer prescribed (4 - 6 week taper period?) and I felt absolutely no change in mood or health.
So apparently I'm more or less immune to effexor. Strange, after thinking it was such a weak drug all these years, I hear how it has such strong effects on people.
...I always felt like I worked out my depression on my own. It was hard as hell, but I had to come to understand a lot of things about life before I could move on. I changed, philosophically. I never felt like that stupid drug helped. Never gave me focus, never made me feel happy or content without reason, never stopped the voice inside from ripping at me.
It didn't help one iota. I have major clinical depression, and am very prone to feelings of self-harm and depression. But they don't last. I understand myself, and can (sometimes) control my intense emotions and feelings of void. Through thought and understanding, I probably appreciate life more than most people I know.
After reading that link provided by outofthepicture, I realise how lucky I am. The one and only immunity I've ever had... ends up saving my sanity.
Ok, my post added nothing to the discussion, and might just upset people more. But it's my experience and I wanted to share it.