i am normally a very calm and quiet person that dont get angry at all ,my friend is often shock by my reaction when i m suppose to be angry but i m not because i can always understand why does people behave the way they do. i changed my anti depressent (mirtazapine ) and put on anti psychotic (quetiapine ) at the same time . but now i am extremely irritable . anything could set me off . i would call people really nasty name when they annoyed me for often a very small matter that i know wouldnt bother me at all before . for example , my sister put one of her clothes into my closest and i shout at her , calling her a 'good for nothing BXXXX' i would said stuff really loud , almost like shouting when people disagree with me . i m still extremely depressed as well as hearing the voice ,i m still on quite a low dose on both of those med . 30mg on mirtazapine and 50 mg on quetiapine . my GP suggested that it will get better when my body is used to the med . i also notice my OCD symptom seems to get worse (i was diagnosis with OCD at one stage but got better ) ,i spend 2-3 hours writing 1 page of information constantly rewrite stuff that i think is not 'on the line' or not neat or when i made a small mistick and i start to take a more bath again ......i dont know if it is because my depression worsen or if it is the med. even if it is cause of the meds i dont know if it is because of the quetiapine or mirtazapine . i been on 25mg quetiapine before but only for a very short time it didnt cause any effect other then drowsiness before i believed it is part of the plan my social worker and dr was plotting against me , i dont have problem with drowsiness now this time . i dont want to waste my time going on other medication but in the same time i dont want to constantly start shouting at people or getting annoyed by extremely small thing , it is something i m not used to and i often feel extremely awkward and embrassed afterward as well as feeling extremely guilty for upsetting those who care more .