I am a 46 year old female and I've had depression on and off throught my adult years, mainly because I have a lot of problems interacting with people. It's like an acute form of social phobia and when I get depressed I become agoraphobic, as has happened now. I feel I look weird/unattractive and that this has had a big effect on how people act towards me. I was also diagnosed with Aspergers Syndrome at age 37 and while this gave some kind of explanation for my problems interacting with people I still feel it's mainly all down to how I look as I've interacted with other people with Aspergers on discussion forums and in real life and none of them seem to have such a problem as myself. I have a malocclusion of the jaw which means my teeth don't meet and it makes my face look long. I feel people judge me as not looking 'normal' enough and it's constantly on my mind. I went to see an orthodontist about having it fixed but he said for all the work they'd have to do the change wouldn't be that noticeable. It's as if the problem isn't taken that seriously by others/not seen as that much of a difference but to me it's a major thing that seems to impact a lot on my interactiosn with others. I have become paranoid and developed a major complex about my face and whatever the truth of the matter I can't change these thoughts. It means I have generally only been leaving the house when I've had to but with the return of my depression I haven't even been able to attend the Drs for the last two appointments and had to have a home visit from the Dr today. She has prescribed a higher dose of my anti-depressants and Diazepam - which I've never taken before. Someone from the chemist is meant to be bringing the medication round today. I feel in a state of depression and near-unbearable agitation and it's worse in the mornings. I feel I've been here so many times before and each time gets worse as my capacity to beat it seems to be wearing out. I want to belive that a higher dose of the anti-depressants and the Diazepam will work but part of me feels it's hopeless.