I have schizo affective disorder and relapsed last year. I had started going to college and doing other 'normal' things and now i'm trapped inside my own head. Whenever a certain medication starts to work I seem to develop side effects that require intervention from the medical doctors. I've been on fluoxetine (stopped working), olanzapine (caused my blood sugar to go too high), risperidone (caused my prolactin to go high) and now i'm on seroquel 800mgs and citalopram 40mg and they don't seem to be working. It's so depressing that I can't just go on a tablet that'd work well and not cause medical problems. The MH team want to put me on venlafaxine and/or lithium and leave me on the seroquel. Has anybody got any experiences with lithium or venlafaxine? I've heard of depakote but apparently that wouldn't be suitable. My other option is ECT which i'd rather not have.