Obviously you have to know what meds will work together & what doesn't. But now my doc has me on diazepam(valium) & xanax simultaneously every day.... mixing in temazepam(restoril) once nightly for sleep. I don't see any problems. In the past I've been written lorazepam(ativan) w/ dyphenhydramine for anxiety/agitation. Then there was the ultimate mixture years ago of Thorazine & clonazepam simultaneously (Klonopin) 3X daily.... for severe agitation. Last, but not least, once upon a time I was given ambien simultaneously w/ trazadone only for sleep. Right now doc is givin my bro 2mg lorazepam + 2 mg clonazepam 4X daily for anger spells. The doctors have never seen any problems with these mixtures that they give out. Aside from developing tolerance issues, do you see a problem with any of these med combos? Should the doctor(s) be bombarded w/ malpractice suits? :laugh: The most addictive ones I've seen ppl take are Lortab + Soma for back pain. Then oxycontin + xanax bars for pain of some other sort(my mom's friend). Do (some) docs go too far?