I have been on 150mg of this for about 2 weeks now. Just wondering if and when people started to notice any effects of it. I have been on Fluoxetine, Citalapram and Sertraline so this is the 4th type in a yr now. Not had any side effects, i dont think anyway. Well only thing is I have had problems with my sleeping for about a month now. I get off to sleep ok but wake about 2 hours later and can not get back to sleep. So I am constantly worn out. I told my doc about this today and he said try taking the pills at night, a couple of hours before bed as may have some sedative effect, yet at the same time the psychiatrist said take them in the morning. What difference does it make if they are the slow release ones anyway. When does everyone else take them?