This is a good topic/question, because many of us are or have been on meds that don't want to be, or are affected negatively by the side effects or cost. This is my take,
I have been on several meds in my life; some helped, some didn't, and some had bad side effects. The first thing I would say is play it safe and follow your doctors orders. Taking medication helps, but sometimes like I said it can hurt in other ways as I've mentioned above, and start to feel like weight that can actually add other problems. I understand the feeling of why you'd want to reduce them. I talked to some in my life who felt 'burdened' that they were attached to a med for whatever reason, and I've felt similar.
I believe it is possible to not have to take something for the rest of one's life, it depends on the person and situation.