I used to get somewhat frequent UTIs. Several in a single year. Then many years passed without them, thank God. But this past December, I got another, probably because I'm on the Skyrizi injection, for psoriasis and Crohn's disease. It compromises the immune system and makes infections more likely and more difficult for the body to fight off. Anyway, I took a course of Cipro and it seemingly went away. Though, I still felt like I was perhaps having some very mild symptoms left over, but I chalked it up as I was imagining things (I probably wasn't). Three weeks later, I knew for certain that the infection was back again full force. I got another course of antibiotics. I felt okay again for about a week. Then it was back again. A freaking third time. And I also realized that it came back right after I injected the Skyrizi. A day or two after. If I knew that would happen, i certainly would have waited to do that. But I only realized after the fact. Took a third course of antibiotics. Nothing. Nothing at all. If anything, I think it got worse. So I was back at the urgent care asking for Cipro again specifically, because the past two times, they had decided to give me a different antibiotic that clearly didn't work as well. So now I'm on my fourth course, and praise God, I think it's starting to work. I was in so much pain from this damn UTI these past two days, especially, that I can't even describe it. All I could do was pray and cry. I'd rather deal with about 20 different kinds of pain than I would this again.