It sounds like mom could use a great deal of help for her own issues, holy crap. She must be really suffering, but it's not okay for her to be taking that out on you. You're not enabling anyone just for saying you won't participate anymore. You are responsible for your actions, and likewise, they are responsible for their own. Any God that would punish you for being on antidepressants - is not worthy of the title, IMHO. I have gotten that also. If I am on medication of any kind, then I am not "sober." Problem is that I was using substances to self medicate so guess what happens when I stop drinking, smoking, and taking pills that weren't prescribed for me. For some, antidepressants are a necessity. Bear in mind that your mom is not a doctor so she doesn't know what she's talking about in that domain. I have been in your situation, and what I did at the time was just withdraw into myself and go into my head. This is not to say that's the best strategy. In hindsight, it has cost me thousands of dollars of therapy to get over. I don't know what the best course is, though. I imagine it has something to do with setting up boundaries and getting your mom to respect those. You said she's not letting you do things. What if you reply with something like, "I'm sorry you don't agree with me, but I'm an adult now and I need to make my own decisions." That way you are not accusing or judging, you're just saying you need your autonomy, which is a basic human right. I have heard that this is common in developmental psychology. Almost every young adult has to come to a critical point where they tell their parents that the child has grown and needs to be treated as an adult. It's just too bad the parents are not even adulting themselves.